Can a Rat Tell You She has a Headache? There’s More to Pain than Molecular Signaling

Registration


There is not a cost to view this online activity. This presentation is part of the Friday Research Seminar Series, was recorded LIVE on September 27, 2013 and is approximately 70 minutes. 

You must login or create an account before enrolling in this educational activity. 

Once you're logged in, please click the "ENTER" button to your right. Your attendance will then be confirmed.

Once you register for the course, you will have 180 days (approximately 6 months) from the date of enrollment to complete the course. The exact date that your access expires will be indicated within the Course Summary box on this webpage.
 

Target Audience

Health professionals.

Objectives

  1. Explain fundamental physiological mechanisms underlying pain sensation, including the spinal and supraspinal centers and systems that process pain and hyperalgesia.
  2. Describe plasticity of the neuronal systems and signals that contribute to sensitization to persistent pain.
  3. Explain sex differences in pain sensation, focusing on effects that estrogen can have to promote sensation.
  4. Describe pain modeling in preclinical studies, focusing on rodent migraine modeling.

Speaker

Kenneth E. McCarson, PhD
Associate Professor, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center

Dr. McCarson has used rodent models of pain and behavioral measures in the study of the neurobiology of pain for well over two decades; as a postdoctoral Research Associate at Washington University these approaches were enhanced by acquiring the molecular tools used to expand my previous studies of the role of neurokinin receptors and tachykinin peptides, linking quantification of behavioral hyperalgesia (pain-related behaviors) with regulation of receptor gene expression in animal models of chronic inflammatory pain. As PI or co-Investigator on numerous university- and NIH-funded grants, I have expanded my studies into additional areas including cutaneous wound healing, GABAB receptor expression and function during pain, the molecular mechanisms underlying gender differences in chronic pain, hippocampal neurogenesis, hippocampal NK-1 receptor and BDNF expression and function, and the relationship between stress and chronic pain. 


Copyright: All rights reserved. By viewing this activity, participants agree to abide by copyright and trademark laws, intellectual property rights, and all other applicable laws of the United States of America. No part of the syllabus may be used or reproduced in any manner whatsoever without written permission, except in the case of brief quotations embodied in articles or reviews.

Internet CME Policy: The Office of Continuing Medical Education (CME) at Des Moines University (DMU) is committed to protecting the privacy of its customers. DMU CME maintains its Internet site as an information resource and service for health professionals. DMU CME will keep your personal and credit information confidential when you participate in an Internet based program. Your information will never be given to anyone outside of the DMU CME program. DMU CME collects only the information necessary to provide you with the services that you request.

Course summary
Available credit: 
  • 1.25 CE Contact Hours
Course opens: 
05/25/2016
Course expires: 
12/31/2018
Cost:
$0.00
IA
United States

Available Credit

  • 1.25 CE Contact Hours

Accreditation Period

Course opens: 
05/25/2016
Course expires: 
12/31/2018

Price

Cost:
$0.00
Please login or Create an Account to take this course.