Dynein Motor Protein Function in Ciliary Motility
Hosted by the Biochemistry and Nutrition department.
Des Moines University faculty, staff, and students.
Disruption in motor protein functioning can lead to debilitating diseases such as Alzheimer’s and motor neuron associated diseases. Dr. Subramanian's research interest lies in understanding the cellular and molecular basis of motor proteins function in cilia and flagella. She uses Tetrahymena thermophila as a model organism to create mutations in motor proteins encoding genes. The mutants created in the lab are analyzed for phenotypic and morphological changes. The results of Dr. Subramanian’s study will contribute to our understanding of ciliary behavior in human disease conditions where access to live cilia for research analysis is not always possible.
Aswati Subramanian, PhD
Assistant Professor of Biology, Simpson College
Dr. Subramanian received her undergraduate degree in Life Sciences and a Master’s degree with a specialization in Neurobiology from Sophia College, Mumbai, India. She joined Miami University, Ohio for her PhD where she studied motor proteins and ciliary motility in Tetrahymena. She continued at Miami as a postdoctoral fellow studying peripheral nerve development in Drosophila. At Simpson, Dr. Subramanian is enthusiastic about conducting undergraduate research on the molecular basis of motility in Tetrahymena. She is also keenly interested in promoting S.T.E.A.M. education by studying areas in which science and art intersect. Outside the classroom she enjoys creating art, cooking, reading and hiking. Full biography.
Des Moines University is located on a 22-acre campus in the heart of Des Moines, Iowa. Just west of downtown on Grand Avenue, the University is located in one of Des Moines' most prestigious neighborhoods. The campus is in a historic neighborhood filled with tree-lined streets and gracious older homes and businesses. Its central location makes it easy to access the rest of the city and outlying communities. The campus is close to the Des Moines International Airport, located on the bus line and just blocks from local shopping and downtown Des Moines.
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